@article {373,
	title = {Multiscale Modeling of Biomolecular Systems: in Serial and in Parallel},
	journal = {Curr Opin Struct Biol},
	volume = {17},
	number = {2},
	year = {2007},
	note = {Ayton, Gary S Noid, Will G Voth, Gregory A 5 F32 GM076839-02/GM/NIGMS NIH HHS/United States GM063796/GM/NIGMS NIH HHS/United States Research Support, N.I.H., Extramural Research Support, U.S. Gov{\textquoteright}t, Non-P.H.S. Review England Current opinion in structural biology Curr Opin Struct Biol. 2007 Apr;17(2):192-8. Epub 2007 Mar 23.},
	pages = {192-8},
	abstract = {<p>Considerable progress has been recently achieved in the multiscale modeling of complex biological processes. Multiscale models have now investigated the structure and dynamics of lipid membranes, proteins, peptides and DNA over length and time scales ranging from the atomic to the macroscopic. Serial multiscale methods that parameterize low-resolution coarse-grained models with data from high-resolution models have studied long time or length scale phenomena that cannot be investigated with atomically detailed models. Parallel multiscale methods that directly couple high- and low-resolution models have efficiently explored slow structural transitions and the importance of long-wavelength fluctuations for biological molecules. The success of such models relies upon new theories and methods for constructing accurate multiscale bridges that transfer information between models with different resolutions.</p>},
	keywords = {Computer Simulation DNA/chemistry Membrane Lipids/chemistry *Models, Molecular Peptides/chemistry Proteins/chemistry *Systems Biology},
	doi = {10.1016/j.sbi.2007.03.004},
	author = {Ayton, G. S. and Noid, W. G. and G. A. Voth}
}
